It is established that the introduction of yeast RNA compounds to the donor animals influences the prolification of colonies of marrow stem cells after their transplantation to the irradiated mice - recipients. The formation of marrow stem cells colonies in donors on the spleen of recipients depends on the concentration, method of introduction, and medical form of yeast RNA. The optimal concentration of exogenous RNA on oral introduction was within 5 - 15 mg per mouse, which - increases the migration of marrow stem cells by 40 - 60 %. The granulated medical form of yeast RNA in a concentration of 3 mg per mouse on oral introduction increased the number of stem cells colonies on recipients' spleen by up to 150 %. However, the highest level of migration of marrow stem cells up to 216 % was established under intravenous introduction of the 3 % injection form of yeast RNA in a concentration of 3 mg per mouse.It is demonstrated that pellets of yeast RNA in optimal concentrations considerably increase the ability of females over 8 months to become pregnant; at the same time, the high indicators of young 5-month-old mice of BALB line are not influenced. The compound reliably increases the average number of baby mice in brood, does not influence the growth of sucker mice, and, at the same time, reliably influences the number of offsprings from young females. Various supplements in RNA pellets reliably increase the average number of baby mice in brood and the number of offsprings from young females.

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