Akyurek S. Role of postmastectomy radiation therapy after neoadjuvant chemotherapy in locally advanced breast cancer / S. Akyurek, G. Yavas // Эксперим. онкология. - 2013. - 35, № 4. - С. 267-271. - Бібліогр.: 35 назв. - англ.Neoadjuvant chemotherapy for primary breast cancer is the gold standard in the treatment of locally advanced, inoperable breast cancer, and also based on a large body of evidence has become a standard treatment option for patients with operable disease, who are clear candidates for adjuvant chemotherapy. There are several advantages of administering neoadjuvant chemotherapy: tumor downstaging, improving the chance of breast conserving surgery, in vivo assessment of tumor sensitivity to the chosen therapeutic regimen, and early control of micro-metastatic disease. However there are substantially less data to aid in determining which patients treated with neo-adjuvant chemotherapy warrant postmastectomy radiotherapy. According to the recent literature, patients who require mastectomy after systemic therapy should receive postmastectomy radiotherapy. Індекс рубрикатора НБУВ: Р569.133.1-5
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