State of Lipid and Fat-Acidic Spectrum of Blood Plasma in the Residents of the Plain Regions of Transcarpathia Depending On Age and Trophological Status

Kedyk, A. V.; Zhulkevych, I. V.

The objective of the study - is to identify the age peculiarities of the fat-acidic and lipid blood plasma spectrum in the inhabitants of the plain settlements of the Transcarpathian region with overweight and obesity. There were examined 107 persons, who applied for the assistance to the Family Medicine Outpatient Clinic № 7 in Uzhgorod. The examined persons were estimated the following data: age, gender, BMI, waist circumference, lipid and fat-acidic spectrum. The study involved 74 women (69,1 %) and 33 men (30,9 %). The average age of the examined persons was <$E52,4~symbol С~1,0> years. The BMI of the examined patients was <$E27,5~symbol С~0,4> kg/m<^>2, and the waist circumference was - <$E92,4~symbol С~1,6> cm. All patients were divided into 6 age groups with intervals of 5 years, starting with 40 years. Starting from the 46 years and older, in each age group, there was a significantly higher BMI compared to persons under 40 years of age. In the examined persons over 40 years the changes of the lipid spectrum in the direction of growth of atherogenic fractions were observed. Beginning from the age of 46 years, the levels of total <$Eomega>6-PUFA and <$Eomega>3-PUFA are significantly higher compared to persons aged under 40 years. In individuals aged under 50 years there is an increase of average levels of PUFA therefore the highest growth of <$Eomega>3-PUFAS is observed in the period from 40 to 50 years of age (from <$E60,10~symbol С~5,50> pg/ml to <$E102,9~symbol С~5,20> <$Emu>g/ml, p << 0,01), and of <$Eomega>6-PUFA in the period from 45 to 50 years (from <$E1288,10~symbol С~62,40> <$Emu>g/ml to <$E1501,10~symbol С~67,50> <$Emu>g/ml; p = 0,03). Conclusions: there is a shift in the lipid spectrum, which corresponds to atherogenic dyslipidemia, in the examined persons aged over 40 years. In individuals aged under 50 years there is an increase in total levels of PUFA, thus the highest growth of <$Eomega>3-PUFA is observed in the period from 40 to 50 years, and <$Eomega>6-PUFA in the period from 45 to 50 years. The stabilization of the fatty acids composition was revealed in persons aged 50 years and more.


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