Postural orthostatic tachycardia syndrome is a condition characterized by imbalance in autonomic reactivity leading to exaggerated heart rate and other symptoms of orthostatic intolerance. In adolescents, it is characterized either by a continuous increase in heart rate of <$Esymbol У~40> bpm as compared to basal heart rate or sustained basal rate of <$Esymbol У~130> bpm. The objective of the research was to compare the characteristics of adolescent diabetics with postural orthostatic tachycardia syndrome with the controls. Seventy adolescents diagnosed with type 1 diabetes mellitus who were treated at the department of Endocrinology, Government Medical College and Shri Maharaja Hari Singh hospital, Srinagar, J&K, India were selected for the study. Lying to standing test was performed. Heart rate was recorded, at the 2<^>nd, 3<^>rd, 5<^>th and 10<^>th minutes. Based on the results of lying to standing test, there were selected 25 diabetic adolescents with postural orthostatic tachycardia syndrome. Their characteristics were compared with age- and sexmatched adolescents using unpaired T test P << 0,05 was considered significant. We observed a significantly lower body mass index (p = 0,027), as well as a significantly higher fasting blood glucose level (p << 0,0001) in diabetics with postural orthostatic tachycardia syndrome. Conclusion: it may be concluded that lower body mass index and higher fasting blood glucose level may lead to the development of postural orthostatic tachycardia syndrome in adolescents.

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