One of the biochemical mechanisms of action of herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) is its influence on the <$E roman {Mg sup 2+ ,Ca sup 2+}>-ATPase activity of hepatocytes plasma membrane after the subchronic introducing into rats (1/40 LD50) and in vitro. Sodium succinate is less active in relation to this enzyme, however it is capable to oppress 2,4-D effects. It can be considered as protective properties of sodium succinate.