Наукова періодика України Міжнародний ендокринологічний журнал


Turgut A. 
Is there any relationship between Hashimoto’s thyroiditis and urinary iodine level? / A. Turgut, M. Erdogan, B. S. Yurekli, E. Sezer, I. Y. Simsir, H. Rouhrazi, N. Turgan // Міжнародний ендокринологічний журнал. - 2019. - Т. 15, № 5. - С. 365-370. - Режим доступу: http://nbuv.gov.ua/UJRN/Mezh_2019_15_5_4
Hashimoto's thyroiditis (HT) is an autoimmune disease which genetic and environmental factors play a role. One of the environmental risk factors is dietary iodine intake. Urinary iodine excretion in balanced diet is equally acceptable with received iodine. It's thought that high urinary iodine excretion was associated with autoimmune thyroid diseases. We purposed to investigate whether urinary iodine level is higher in patients with HT than population. 64 new patients with HT and 39 healthy volunteers were included. Age, gender, serum free-triiodothyronine (fT3), free-thyroxine (fT4), thyroid-stimulating hormone (TSH), anti thyroid peroxidase antibody (anti-TPO), anti thyroglobulin antibody (anti-TG) and urinary iodine concentration (UIC) were evaluated. Thyroid ultrasonography was performed. UIC were measured by Sandell-Kolthoff method. There was no significant relationship was found between total thyroid volume and UIC in our study (p >> 0,05). There was no significant difference between the fT3, fT4, anti-TPO, anti-TG and thyroid volume values of the individuals with urinary iodine levels below and above 100 g/L. The difference between two subgroups was found to be significant only when TSH values were compared (p = 0,04). There was no significant difference between total thyroid volumes. No relation was found between HT and urine iodine levels in our study. The fact that the prevalence of HT in our country is similar to the literature makes us question the role of dietary iodine in the etiology. Conclusions. At the iodine-deficient regions such as our country relationship between urinary iodine excretion and HT needs to be investigated.
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Цитованість авторів публікації:
  • Turgut A.
  • Erdogan M.
  • Yurekli B.
  • Sezer E.
  • Simsir I.
  • Rouhrazi H.
  • Turgan N.

  • Бібліографічний опис для цитування:

    Turgut A. Is there any relationship between Hashimoto’s thyroiditis and urinary iodine level? / A. Turgut, M. Erdogan, B. S. Yurekli, E. Sezer, I. Y. Simsir, H. Rouhrazi, N. Turgan // Міжнародний ендокринологічний журнал. - 2019. - Т. 15, № 5. - С. 365-370. - Режим доступу: http://nbuv.gov.ua/UJRN/Mezh_2019_15_5_4.

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